Heather Francis Selected Research

Fast Green

1/2021	Mast Cells Induce Ductular Reaction Mimicking Liver Injury in Mice Through Mast Cell-Derived Transforming Growth Factor Beta 1 Signaling.
1/2020	Amelioration of Large Bile Duct Damage by Histamine-2 Receptor Vivo-Morpholino Treatment.
10/2016	Inhibition of mast cell-secreted histamine decreases biliary proliferation and fibrosis in primary sclerosing cholangitis Mdr2(-/-) mice.

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Heather Francis Research Topics

Disease

33	Fibrosis (Cirrhosis) 01/2022 - 08/2006
28	Cholangiocarcinoma 04/2021 - 06/2002
27	Cholestasis 11/2021 - 05/2002
26	Liver Cirrhosis (Hepatic Cirrhosis) 01/2022 - 09/2012
26	Neoplasms (Cancer) 01/2022 - 12/2005
25	Inflammation (Inflammations) 01/2022 - 10/2004
18	Liver Diseases (Liver Disease) 01/2022 - 10/2004
16	Hyperplasia 01/2022 - 05/2007
11	Sclerosing Cholangitis 03/2022 - 06/2004
11	Non-alcoholic Fatty Liver Disease 01/2022 - 01/2018
7	Alcoholic Liver Diseases (Alcoholic Liver Disease) 01/2021 - 09/2012
6	Fatty Liver 10/2021 - 02/2014
5	Carcinogenesis 01/2021 - 08/2008
4	Body Weight (Weight, Body) 01/2019 - 08/2009
4	Necrosis 10/2014 - 10/2004
3	Obesity 01/2022 - 01/2018
3	Insulin Resistance 01/2021 - 01/2019
3	Liver Neoplasms (Liver Cancer) 01/2021 - 12/2011
3	Hepatocellular Carcinoma (Hepatoma) 01/2018 - 08/2008
3	Ischemia 01/2018 - 11/2007
2	Alcoholic Fatty Liver 01/2022 - 01/2020
2	Neoplasm Metastasis (Metastasis) 07/2021 - 11/2011
2	Disease Progression 11/2020 - 01/2018
2	Wounds and Injuries (Trauma) 04/2020 - 01/2018
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2019 - 01/2018
2	Pancreatic Neoplasms (Pancreatic Cancer) 08/2013 - 01/2013

Drug/Important Bio-Agent (IBA)

19	Histamine (Histamine Dihydrochloride)FDA Link 03/2022 - 06/2010
13	Secretin FDA Link 10/2021 - 04/2003
13	MicroRNAs (MicroRNA)IBA 11/2020 - 12/2011
12	Bile Acids and Salts (Bile Acids)IBA 03/2022 - 05/2002
12	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 12/2005
9	MelatoninIBA 01/2022 - 10/2011
9	secretin receptorIBA 10/2021 - 04/2010
8	Proteins (Proteins, Gene)FDA Link 11/2020 - 05/2007
6	LipidsIBA 10/2021 - 04/2007
6	MorpholinosIBA 11/2020 - 07/2017
6	Biological ProductsIBA 01/2020 - 01/2007
6	Histamine Receptors (Histamine Receptor)IBA 01/2018 - 10/2009
5	CollagenIBA 01/2022 - 12/2005
5	Phosphotransferases (Kinase)IBA 01/2021 - 07/2013
5	Messenger RNA (mRNA)IBA 11/2020 - 05/2006
5	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 01/2018
5	Bicarbonates (Hydrogen Carbonate)IBA 01/2019 - 11/2004
5	Hormones (Hormone)IBA 01/2019 - 07/2007
5	Histidine DecarboxylaseIBA 10/2016 - 05/2012
4	Adrenergic Agents (Adrenergic Drugs)IBA 01/2022 - 06/2002
4	CytokinesIBA 01/2021 - 07/2003
4	FructoseIBA 01/2021 - 01/2018
4	Substance PIBA 11/2020 - 08/2011
4	Vascular Endothelial Growth Factor CIBA 01/2020 - 12/2005
4	Proliferating Cell Nuclear Antigen (PCNA)IBA 05/2014 - 07/2010
3	Fast GreenIBA 01/2021 - 10/2016
3	Protein Kinases (Protein Kinase)IBA 01/2021 - 10/2009
3	Neurokinin-1 Receptors (Neurokinin 1 Receptor)IBA 11/2020 - 08/2011
3	Histidine (L-Histidine)FDA Link 01/2020 - 01/2018
3	Carboxy-LyasesIBA 01/2020 - 01/2018
3	Arylalkylamine N-AcetyltransferaseIBA 01/2019 - 11/2014
3	Adenosine (Adenocard)FDA LinkGeneric 01/2018 - 05/2007
3	EnzymesIBA 10/2017 - 05/2012
3	Cromolyn Sodium (Cromoglicic Acid)FDA LinkGeneric 11/2016 - 01/2016
3	Chloride-Bicarbonate AntiportersIBA 07/2013 - 04/2010
3	EndocannabinoidsIBA 12/2008 - 04/2007
2	indoleIBA 01/2022 - 10/2020
2	Melatonin Receptors (Melatonin Receptor)IBA 01/2022 - 10/2011
2	Cholinergic Agents (Cholinergics)IBA 01/2022 - 10/2007
2	Adenosine Monophosphate (AMP)IBA 01/2022 - 07/2013
2	Methionine (L-Methionine)FDA Link 01/2022 - 10/2021
2	Choline (Choline Chloride)IBA 01/2022 - 10/2021
2	Taurocholic Acid (Sodium Taurocholate)IBA 01/2022 - 05/2007
2	Biomarkers (Surrogate Marker)IBA 07/2021 - 01/2021
2	Insulin (Novolin)FDA Link 01/2021 - 01/2019
2	SynaptophysinIBA 01/2021 - 10/2016
2	Cyclic AMP (AMP, Cyclic)IBA 01/2021 - 12/2005
2	DesminIBA 01/2021 - 01/2020
2	Transforming Growth Factor beta (TGF-beta)IBA 01/2021 - 10/2016
2	Small Interfering RNA (siRNA)IBA 11/2020 - 10/2016
2	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2020 - 04/2020
2	Serotonin (5 Hydroxytryptamine)IBA 01/2020 - 01/2005
2	VimentinIBA 01/2020 - 10/2019
2	LipopolysaccharidesIBA 01/2020 - 12/2018
2	Monoamine Oxidase (MAO)IBA 01/2020 - 05/2012
2	Stem Cell FactorIBA 12/2019 - 01/2016
2	Mitogen-Activated Protein KinasesIBA 01/2019 - 10/2009
2	ATP-Binding Cassette Sub-Family B Member 4IBA 01/2019 - 01/2017
2	Histamine Antagonists (Antihistamines)IBA 01/2019 - 06/2010
2	NF-kappa B (NF-kB)IBA 01/2019 - 08/2009
2	LeptinIBA 01/2018 - 08/2008
2	Ethanol (Ethyl Alcohol)IBA 12/2017 - 02/2014
2	Gonadotropin-Releasing Hormone (GnRH)FDA Link 07/2017 - 04/2015
2	salicylhydroxamic acid (SHAM)IBA 01/2017 - 08/2011
2	3- ((3,5- bis(trifluoromethyl)phenyl)methyloxy)- 2- phenylpiperidineIBA 01/2017 - 05/2014
2	ChemokinesIBA 01/2016 - 08/2009

Therapy/Procedure

16	Ligation 01/2019 - 10/2004
13	Therapeutics 12/2021 - 06/2007
3	Denervation 01/2022 - 05/2007
2	Immunotherapy 01/2022 - 01/2020
2	Drug Therapy (Chemotherapy) 07/2021 - 09/2013
2	Aftercare (After-Treatment) 11/2018 - 05/2011
2	Lasers (Laser) 01/2018 - 01/2017
2	Liver Transplantation 12/2015 - 08/2010